Bedbugs pierce the skin of its host with its mouth part and injects saliva which is a mixture of an anesthetic (host feels nothing), and an anticoagulant (blood flows out freely). It then sucks out blood until it is full. The bites are not noticeable until after the skin reaction has occurred. CDC reported that bedbugs take up to 14 days trusted source for bites to appear. A bed bug bite affects each person differently. Bite responses can range from an absence of any physical signs of the bite, to a small bite mark, to a serious allergic reaction. Bed bugs are not considered to be dangerous. Bed bugs are not known to spread disease but can be an annoyance because their presence may cause itching and loss of sleep.
